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Photo of Dan Bonthius

Dan Bonthius

Professor,  Pediatrics

Contact Information

Professor of Pediatrics and Neurology; Director, Child Neurology Residency Program
2500 JCP
Iowa City, IA 52242

Phone: +1 319 356 1851
Email: daniel-bonthius@uiowa.edu
Web: University of Iowa Healthcare web page

Education

BS, Zoology, The University of Iowa, Iowa City IA
MD, Medical Doctor, The University of Iowa, Iowa City IA
PhD, Neuroscience, The University of Iowa, Iowa City, IA
Fellowship, Neuroscience and Pediatrics, University of Virginia
Residency, Pediatric Neurology, University of Iowa Children's Hospital

Appointments

Primary: Pediatrics
Secondary: Neurology

Centers and Program Affiliations

Interdisciplinary Graduate Program in Molecular and Cellular Biology
Interdisciplinary Graduate Program in Neuroscience

Research Interests

birth or congenital defect, brain development, epilepsy, fetal alcohol syndrome, neurology, pediatrics

MeSH Terms from Publications

Ethanol, Cerebellum, Animals, Neurons, Rats, Animals, Newborn, Central Nervous System Depressants, Lymphocytic Choriomeningitis, Fetal Alcohol Syndrome, Brain, Male, Female, Hippocampus, Nitric Oxide Synthase Type I, Cortical Spreading Depression, Pregnancy, Cell Count, Lymphocytic choriomeningitis virus, Body Weight, Rats, Sprague-Dawley, Humans, Rats, Inbred Strains, Microcephaly, Olfactory Bulb, Mice, Knockout

Research Summary

Neuroteratogenic changes induced by lymphocytic choriomeningitis virus infection Fetal alcohol syndrome Brain development and plasticity Neurologic birth defects induced by environmental agents Pediatric epilepsy

Recent Publications


Show publications
  1. Bonthius, D. Ataxia and the cerebellum. Semin Pediatr Neurol 18(2):69-71, 2011. [PubMed]
  2. Henry, D, Bonthius, D. Isolated musculocutaneous neuropathy in an adolescent baseball pitcher. J Child Neurol 26(12):1567-70, 2011. [PubMed]
  3. Bonthius, DJ, Mahoney, J, Karacay, B. EVIDENCE FROM AN ANIMAL MODEL THAT GENETICS INFLUENCES SUSCEPTIBILITY TO FETAL ALCOHOL SYNDROME. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 35(6):43A-43A, JUN 2011.
  4. Karacay, B, Mahoney, J, Bonthius, DJ. ROLIPRAM, A PHOSPHODIESTERASE INHIBITOR, PROTECTS DEVELOPING NEURONS AGAINST ALCOHOL-INDUCED CELL DEATH. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 35(6):36A-36A, JUN 2011.
  5. Bonthius, D. Lymphocytic choriomeningitis virus: a prenatal and postnatal threat. Adv Pediatr 56:75-86, 2009. [PubMed]
  6. de Licona, H, Karacay, B, Mahoney, J, McDonald, E, Luang, T, Bonthius, D. A single exposure to alcohol during brain development induces microencephaly and neuronal losses in genetically susceptible mice, but not in wild type mice. Neurotoxicology 30(3):459-70, 2009. [PubMed]
  7. Bonthius, D, Luong, T, Bonthius, N, Hostager, B, Karacay, B. Nitric oxide utilizes NF-kappaB to signal its neuroprotective effect against alcohol toxicity. Neuropharmacology 56(3):716-31, 2009. [PubMed]
  8. Bonthius, DJ, Luong, T, Bonthius, NE, Hostager, BS, Karacay, B. TNF-alpha AND NMDA ACTIVATE NF-kappa B TO PROTECT DEVELOPING NEURONS AGAINST ALCOHOL TOXICITY. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 33(6):164A-164A, JUN 2009.
  9. Bonthius, DJ, Luong, T, Bonthius, NE, Hostager, BS, Karacay, B. Nitric oxide utilizes NF-kappa B to signal its neuroprotective effect against alcohol toxicity. NEUROPHARMACOLOGY 56(3):716-731, MAR 2009.
  10. Bonthius, DJ, Rabe, G, de Licona, HWK, Ordoubadian, A, Karacay, B. Congenital LCM Virus Infection can Induce Cerebellar Hypoplasia in Humans: an Animal Model Reveals its Mechanisms.. ANNALS OF NEUROLOGY 66(null):S100-S100, 2009.