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Photo of John Buatti

John Buatti

Professor,  Radiation Oncology

Contact Information

Phone: +1 319 356 2699
Email: john-buatti@uiowa.edu
Web:

Education

BS, Biology/Theology, Georgetown University, Washington, D.C.
MD, Medicine, Georgetown University, Washington, D.C.

Appointments

Primary: Radiation Oncology
Secondary: Otolaryngology - Head & Neck Surgery
Secondary: Neurosurgery

Centers and Program Affiliations


Research Interests

Quantitative Imaging, tumor response to therapy, Thymadine, Head and Neck Cancer, Glioblastoma Multiforme, Anaplastic Astrochytoma, Temozolomide

MeSH Terms from Publications

Head and Neck Neoplasms, Radiotherapy, Conformal, Radiotherapy Dosage, Humans, Carcinoma, Squamous Cell, Radiopharmaceuticals, Brain Neoplasms, Radiosurgery, Middle Aged, Radiotherapy Planning, Computer-Assisted, Fluorodeoxyglucose F18, Male, Female, Positron-Emission Tomography, Aged, Lymphatic Metastasis, Combined Modality Therapy, Adult, Radiometry, Treatment Failure, Neck Dissection, Radiotherapy, Intensity-Modulated, Retrospective Studies, Radiotherapy, Computer-Assisted, Magnetic Resonance Imaging

Research Summary

The focus of my research is the use of imaging to improve outcomes for patients undergoing cancer therapy, radiation therapy in particular.

Grants that I am a part of that support this focus are:

  1. U01 CA140206 Quantitative Imaging to Assess Response in Cancer Therapy Trials and
  2. R21 CA130281 Imaging Thymidine Uptake During Treatment for Head and Neck Cancer

Other areas of interest are in treating cancers of the Head and Neck and Brain, especially in the pediatric population.



Recent Publications


Show publications
  1. Bayouth, J, Casavant, T, Graham, M, Sonka, M, Muruganandham, M, Buatti, J. Image-based biomarkers in clinical practice. Semin Radiat Oncol 21(2):157-66, 2011. [PubMed]
  2. Menda, Y, Ponto, L, Dornfeld, K, Tewson, T, Watkins, G, Gupta, A, Anderson, C, McGuire, S, Schultz, M, Sunderland, J, Graham, M, Buatti, J. Investigation of the pharmacokinetics of 3'-deoxy-3'-[18F]fluorothymidine uptake in the bone marrow before and early after initiation of chemoradiation therapy in head and neck cancer. Nucl Med Biol 37(4):433-8, 2010. [PubMed]
  3. Ding, K, Bayouth, J, Buatti, J, Christensen, G, Reinhardt, J. 4DCT-based measurement of changes in pulmonary function following a course of radiation therapy. Med Phys 37(3):1261-72, 2010. [PubMed]
  4. Mayr, N, Yuh, W, Jajoura, D, Wang, J, Lo, S, Montebello, J, Porter, K, Zhang, D, McMeekin, D, Buatti, J. Ultra-early predictive assay for treatment failure using functional magnetic resonance imaging and clinical prognostic parameters in cervical cancer. Cancer 116(4):903-12, 2010. [PubMed]
  5. Gupta, A, Wilke, W, Taylor, E, Bodeker, K, Hoffman, H, Milhem, M, Buatti, J, Robinson, R. Signaling pathways in adenoid cystic cancers: implications for treatment. Cancer Biol Ther 8(20):1947-51, 2009. [PubMed]
  6. Menda, Y, Boles Ponto, L, Dornfeld, K, Tewson, T, Watkins, G, Schultz, M, Sunderland, J, Graham, M, Buatti, J. Kinetic analysis of 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-FLT) in head and neck cancer patients before and early after initiation of chemoradiation therapy. J Nucl Med 50(7):1028-35, 2009. [PubMed]
  7. Gupta, A, Lee, J, Wilke, W, Quon, H, Smith, G, Maity, A, Buatti, J, Spitz, D. Radiation response in two HPV-infected head-and-neck cancer cell lines in comparison to a non-HPV-infected cell line and relationship to signaling through AKT. Int J Radiat Oncol Biol Phys 74(3):928-33, 2009. [PubMed]
  8. Yao, M, Smith, R, Hoffman, H, Funk, G, Lu, M, Menda, Y, Graham, M, Buatti, J. Clinical significance of postradiotherapy [18F]-fluorodeoxyglucose positron emission tomography imaging in management of head-and-neck cancer-a long-term outcome report. Int J Radiat Oncol Biol Phys 74(1):9-14, 2009. [PubMed]
  9. Sato, T, Kirby, P, Buatti, J, Moritani, T. Papillary tumor of the pineal region: report of a rapidly progressive tumor with possible multicentric origin. Pediatr Radiol 39(2):188-90, 2009. [PubMed]
  10. Bylund, K, Bayouth, J, Smith, M, Hass, A, Bhatia, S, Buatti, J. Analysis of interfraction prostate motion using megavoltage cone beam computed tomography. Int J Radiat Oncol Biol Phys 72(3):949-56, 2008. [PubMed]