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Photo of Eugene Chang

Eugene Chang

Assistant Professor,  Otolaryngology - Head & Neck Surgery

Contact Information

Phone: +1 319 384 6865
Email: eugene-chang@uiowa.edu
Web:

Education

BA, Economics, Brown University
MD, Medicine, Brown Medical School
Post-Doc, Genetics of Hearing, Molecular Otolaryngology Research Laboratory
Residency, Otolaryngology, University of Iowa Hospitals & Clinics
Post-Doc, Sinopulmonary airway research, University of Iowa Hospitals & Clinics

Appointments

Primary: Otolaryngology - Head & Neck Surgery

Centers and Program Affiliations


Research Interests


MeSH Terms from Publications

Amelogenesis, Branchio-Oto-Renal Syndrome, Antiporters, Anion Transport Proteins, Sus scrofa, Dental Enamel, Protein Tyrosine Phosphatases, Deafness, Mutant Proteins, Mutation, Humans, Cystic Fibrosis Transmembrane Conductance Regulator, Peritonsillar Abscess, Genetic Testing, Head-Down Tilt, Cystic Fibrosis, Intracellular Signaling Peptides and Proteins, Velopharyngeal Insufficiency, Tryptases, Rats, Wistar, Trans-Activators, POU Domain Factors, Sodium-Bicarbonate Symporters, Patient Satisfaction, Nuclear Proteins

Research Summary



Recent Publications


Show publications
  1. Lacruz, R, Smith, C, Moffatt, P, Chang, E, Bromage, T, Bringas, P, Nanci, A, Baniwal, S, Zabner, J, Welsh, M, Kurtz, I, Paine, M. Requirements for ion and solute transport, and pH regulation during enamel maturation. J Cell Physiol 227(4):1776-85, 2012. [PubMed]
  2. Brian J. Dlouhy, M.D., Karthik Madhavan, M.D., John D. Clinger, M.D., Ambur Reddy, M.D., Jeffrey D. Dawson, Sc.D., Erin K O’Brien, M.D., Eugene Chang, M.D., Scott M. Graham, M.D., and Jeremy D. W. Greenlee, M.D. “Elevated Body Mass Index Increases Risk of Postoperative CSF Leak Following Transsphenoidal Surgery.” Journal of Neurosurgery. accepted Jan 2012

  3. Chang, E, Lacruz, R, Bromage, T, Bringas, P, Welsh, M, Zabner, J, Paine, M. Enamel pathology resulting from loss of function in the cystic fibrosis transmembrane conductance regulator in a porcine animal model. Cells Tissues Organs 194(2-4):249-54, 2011. [PubMed]
  4. Chang, E, Pezzulo, A, Zabner, J. Do cell junction protein mutations cause an airway phenotype in mice or humans? Am J Respir Cell Mol Biol 45(2):202-20, 2011. [PubMed]
  5. Stoltz, D, Meyerholz, D, Pezzulo, A, Ramachandran, S, Rogan, M, Davis, G, Hanfland, R, Wohlford-Lenane, C, Dohrn, C, Bartlett, J, Nelson, G, Chang, E, Taft, P, Ludwig, P, Estin, M, Hornick, E, Launspach, J, Samuel, M, Rokhlina, T, Karp, P, Ostedgaard, L, Uc, A, Starner, T, Horswill, A, Brogden, K, Prather, R, Richter, S, Shilyansky, J, McCray, P, Zabner, J, Welsh, M. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Sci Transl Med 2(29):29ra31, 2010. [PubMed]
  6. Chang, E, Lee, J, Zabner, J. Tryptase does not alter transepithelial conductance or paracellular permeability in human airway epithelial cells. Am J Rhinol Allergy 24(2):126-8, 0. [PubMed]
  7. Chang, E, Lobe, T, Wright, S. Our initial experience of the transaxillary totally endoscopic approach for hemithyroidectomy. Otolaryngol Head Neck Surg 141(3):335-9, 2009. [PubMed]
  8. Chang, E, Hamilton, G. Novel technique for peritonsillar abscess drainage. Ann Otol Rhinol Laryngol 117(9):637-40, 2008. [PubMed]
  9. Vore, A, Chang, E, Hoppe, J, Butler, M, Forrester, S, Schneider, M, Smith, L, Burke, D, Campbell, C, Smith, R. Deletion of and novel missense mutation in POU3F4 in 2 families segregating X-linked nonsyndromic deafness. Arch Otolaryngol Head Neck Surg 131(12):1057-63, 2005. [PubMed]
  10. Husein, M, Chang, E, Cable, B, Karnell, M, Karnell, L, Canady, J. Outcomes for children with submucous cleft palate and velopharyngeal insufficiency. J Otolaryngol 33(4):222-6, 2004. [PubMed]