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Photo of Polly Ferguson

Polly Ferguson

Associate Professor,  Pediatrics

Contact Information

Department of Pediatrics
4040 BT
Iowa City, IA 52242

Phone: +1 319 356 1608
Email: polly-ferguson@uiowa.edu
Web:

Education

BS, University of Iowa
MD, Pediatrics, University of Iowa Carver College of Medicine
Internship, Pediatrics, University of Virginia
Residency, Pediatrics, University of Virginia
Fellowship, Pediatric Rheumatology & Immunology, University of Virginia
Post-Doc, Research Fellow, University of Virginia

Appointments

Primary: Pediatrics

Centers and Program Affiliations


Research Interests

arthritis, inflammation, lupus, pediatrics

MeSH Terms from Publications

Osteomyelitis, Humans, Thymidylate Synthase, Antimetabolites, Antineoplastic, Animals, Vincristine, Pedigree, HeLa Cells, Erythrocytes, Receptors, Complement, Carcinoma, Squamous Cell, Mice, Drug Resistance, Macaca mulatta, Female, Mutation, Male, Floxuridine, Formycins, Autoantibodies, Nuclear Proteins, Nucleoside Transport Proteins, Head and Neck Neoplasms, Antineoplastic Agents, Chronic Disease

Research Summary

Clinical Interests: Inflammatory Disorders in Childhood including all forms of Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, Vasculitis Syndromes and rare inflammatory conditions including Chronic Recurrent Multifocal Osteomyelitis, SAPHO Syndrome and Periodic Fever Syndromes. Research Interests: Genetic Aspects of Inflammatory Disorders, current research projects focus on determining the genetic basis of Chronic Recurrent Multifocal Osteomyelitis, SAPHO Syndrome and Lupus.

Recent Publications


Show publications
  1. Development of consensus treatment plans for juvenile localized scleroderma: a roadmap toward comparative effectiveness studies in juvenile localized scleroderma. Arthritis Care Res (Hoboken) 64(8):1175-85, 2012. [PubMed]
  2. Current understanding of the pathogenesis and management of chronic recurrent multifocal osteomyelitis. Curr Rheumatol Rep 14(2):130-41, 2012. [PubMed]
  3. A novel mutation of IL1RN in the deficiency of interleukin-1 receptor antagonist syndrome: description of two unrelated cases from Brazil. Arthritis Rheum 63(12):4007-17, 2011. [PubMed]
  4. Combining small interfering RNAs targeting thymidylate synthase and thymidine kinase 1 or 2 sensitizes human tumor cells to 5-fluorodeoxyuridine and pemetrexed. J Pharmacol Exp Ther 338(3):952-63, 2011. [PubMed]
  5. Mutations in prickle orthologs cause seizures in flies, mice, and humans. Am J Hum Genet 88(2):138-49, 2011. [PubMed]
  6. Primed innate immunity leads to autoinflammatory disease in PSTPIP2-deficient cmo mice. Blood 114(12):2497-505, 2009. [PubMed]
  7. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. N Engl J Med 360(23):2426-37, 2009. [PubMed]
  8. Papular xanthomas and erosive arthritis in a 3 year old girl, is this a new MRH variant? Pediatr Rheumatol Online J 7:15, 2009. [PubMed]
  9. Primary multifocal osseous lymphoma in a child. Pediatr Radiol 38(12):1338-41, 2008. [PubMed]
  10. A homozygous mutation in human PRICKLE1 causes an autosomal-recessive progressive myoclonus epilepsy-ataxia syndrome. Am J Hum Genet 83(5):572-81, 2008. [PubMed]