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Photo of Michael Goodheart

Michael J Goodheart

Assistant Professor,  Obstetrics & Gynecology

Contact Information

Phone:
Email: michael-goodheart@uiowa.edu
Web:

Education

BA, Chemistry, North Carolina State University, Raleighm NC
MD, Medicine, East Carolina University School of Medicine, Greenville, NC
Residency, Obstetrics and Gynecology, Louisana State University School of Medicine, New Orleans, LA
Residency, Surgery, University of South Florida School of Medicine, Tampa FL
Fellowship, Gynecologic Oncology Laboratory, University of Iowa Hospitals and Clinics, Iowa City, IA
Fellowship, Gynecologic Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA

Appointments

Primary: Obstetrics & Gynecology
Secondary: Anatomy & Cell Biology

Centers and Program Affiliations


Research Interests


MeSH Terms from Publications

Ovarian Neoplasms, Female, Humans, Middle Aged, Genes, p53, Gene Expression Regulation, Neoplastic, Uterine Cervical Neoplasms, Wnt3A Protein, Aged, Social Support, Lymphoid Enhancer-Binding Factor 1, Wnt3 Protein, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Aged, 80 and over, Neovascularization, Pathologic, Antigens, CD31, CA-125 Antigen, Ferrets, Carcinoma, Neoplasm Staging, Wnt Proteins, Endometrial Neoplasms, Prognosis, Thromboembolism, Mutation

Research Summary

Relating p53 mutation types to angiogenesis and immunohistochemical expression in epithelial ovarian cancers, and mutations of the BRCA2 gene in ovarian cancers. 

Transcriptional regulation of the lymphoid enhancer factor-1 (Lef-1) promoter and its relevance in the pathogenesis of ovarian and endometrial cancer.

 



Recent Publications


Show publications
  1. Sleep disturbance, cytokines, and fatigue in women with ovarian cancer. Brain Behav Immun 26(7):1037-44, 2012. [PubMed]
  2. Intraoperative autologous blood transfusion use during radical hysterectomy for cervical cancer: long-term follow-up of a prospective trial. Arch Gynecol Obstet 286(3):717-21, 2012. [PubMed]
  3. Social influences on clinical outcomes of patients with ovarian cancer. J Clin Oncol 30(23):2885-90, 2012. [PubMed]
  4. Incidence and management of gastrointestinal perforation from bevacizumab in advanced cancers. Curr Oncol Rep 14(4):277-84, 2012. [PubMed]
  5. Endometrial cancer. Obstet Gynecol Clin North Am 39(2):255-68, 2012. [PubMed]
  6. The role of LEF1 in endometrial gland formation and carcinogenesis. PLoS One 7(7):e40312, 2012. [PubMed]
  7. microRNA expression profiling of endometrial endometrioid adenocarcinomas and serous adenocarcinomas reveals profiles containing shared, unique and differentiating groups of microRNAs. Oncol Rep 26(4):995-1002, 2011. [PubMed]
  8. A single-institution evaluation of factors important in fallopian tube carcinoma recurrence and survival. Int J Gynecol Cancer 21(7):1232-40, 2011. [PubMed]
  9. CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice. J Clin Invest 121(8):3144-58, 2011. [PubMed]
  10. Selective suppression of cervical cancer Hela cells by 2-O-?-D-glucopyranosyl-L-ascorbic acid isolated from the fruit of Lycium barbarum L. Cell Biol Toxicol 27(2):107-21, 2011. [PubMed]