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Jonathan Klein

Associate Professor,  Pediatrics

Contact Information

Phone: +1 319 356 3340
Email: jonathan-klein@uiowa.edu
Web:

Education

BA, Johns Hopkins University
MD, Medical College of Virginia
Residency, Pediatrics, Children's Medical Center of Dallas
Fellowship, Neonatology, Tufts University

Appointments

Primary: Pediatrics

Centers and Program Affiliations


Research Interests

EGF, epidermal growth factor, fetal lung development, growth factor, infant, infant morbidity, infant mortality, newborn, pediatrics, pulmonary disease, pulmonary immaturity, RDS, respiratory distress syndrome, respiratory system, stimulated lung development, surfactant deficiency

MeSH Terms from Publications

Pulmonary Surfactants, Humans, Pulmonary Surfactant-Associated Proteins, Invertebrate Hormones, Proteolipids, Brachyura, Infant, Newborn, Pulmonary Surfactant-Associated Protein A, Male, Female, Animals, Siphonaptera, Lung, Indian Ocean Islands, Madagascar, High-Frequency Ventilation, Ticks, Receptor, Epidermal Growth Factor, Cambodia, Respiratory Distress Syndrome, Newborn, Protein Precursors, Fetal Organ Maturity, RNA, Messenger, Pregnancy, Epidermal Growth Factor

Research Summary

My clinical and research interests include high-frequency ventilation, nitric oxide therapy, surfactant replacement therapy, persistent pulmonary hypertension of the newborn, sex-specific differences in lung development, and the effects of epidermal growth factor on lung development.

Recent Publications


Show publications
  1. Prediction of survival in infants with congenital diaphragmatic hernia based on stomach position, surgical timing, and oxygenation index. Am J Perinatol 29(5):383-90, 2012. [PubMed]
  2. Improving survival of extremely preterm infants born between 22 and 25 weeks of gestation. Obstet Gynecol 119(4):795-800, 2012. [PubMed]
  3. Variations in CRHR1 are associated with persistent pulmonary hypertension of the newborn. Pediatr Res 71(2):162-7, 2012. [PubMed]
  4. Nasal high-frequency ventilation for premature infants. Acta Paediatr 97(11):1518-22, 2008. [PubMed]
  5. 11-Beta hydroxysteroid dehydrogenase type 2 in human adult and fetal lung and its regulation by sex steroids. Pediatr Res 62(1):26-31, 2007. [PubMed]
  6. Periventricular leukomalacia and prenatal methamphetamine exposure: a case report. Am J Perinatol 24(2):123-6, 2007. [PubMed]
  7. Repeat surfactant therapy for postsurfactant slump. J Perinatol 26(7):414-22, 2006. [PubMed]
  8. Glucocorticoid metabolism in the human fetal lung: implications for lung development and the pulmonary surfactant system. Biol Neonate 89(2):109-19, 2006. [PubMed]
  9. Controversy surrounding the use of home oxygen for premature infants with bronchopulmonary dysplasia. J Perinatol 24(1):36-40, 2004. [PubMed]
  10. Oxygen-saturation targets in extremely preterm infants. N Engl J Med 349(24):2362; author reply 2362, 2003. [PubMed]