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Photo of Andrew Norris

Andrew Norris

Associate Professor,  Pediatrics

Contact Information

Phone: +1 319 335 7383
Email: andrew-norris@uiowa.edu
Web:

Education

BS, Chemistry, Massachusetts Institute of Technology
PhD, Molecular Biology, Washington University School of Medicine, St. Louis
MD, Medicine, Washington University School of Medicine, St. Louis
Residency, Pediatrics, University of Iowa Hospitals & Clinics
Fellowship, Pediatric Endocrinology, Joslin Daibetes Center, Boston Children's Hospital
Post-Doc, Diabetes Research, Joslin Diabetes Center

Appointments

Primary: Pediatrics
Secondary: Biochemistry

Centers and Program Affiliations

Interdisciplinary Graduate Program in Informatics

Research Interests

diabetes, epigenetics, fetal development, fetal programming, insulin resistance, lipid metabolism, pediatrics, PPAR, skeletal muscle

MeSH Terms from Publications

Receptors, Retinoic Acid, Tretinoin, Animals, Retinoid X Receptors, Mice, Fatty Acid-Binding Proteins, 8,11,14-Eicosatrienoic Acid, Transcription Factors, Molecular Conformation, Spectrometry, Fluorescence, Acitretin, Adipose Tissue, White, Anilino Naphthalenesulfonates, Rats, Titrimetry, Mice, Obese, Hydroxyeicosatetraenoic Acids, Linoleic Acid, Retinoids, Fatty Acids, PPAR gamma, Adipocytes, Neoplasm Proteins, Mice, Inbred C57BL, Insulin

Research Summary

My research interests include: diabetes / lipid metabolism interactions; epigenetic features of youth-onset type 2 diabetes; transcriptional phenomena related to diabetes.

Recent Publications


Show publications
  1. Norris, A, Wang, C, Yao, J, Walsh, S, Sawatzke, A, Hu, S, Sunderland, J, Segar, J, Ponto, L. Effect of insulin and dexamethasone on fetal assimilation of maternal glucose. Endocrinology 152(1):255-62, 2011. [PubMed]
  2. Joss-Moore, L, Wang, Y, Baack, M, Yao, J, Norris, A, Yu, X, Callaway, C, McKnight, R, Albertine, K, Lane, R. IUGR decreases PPAR? and SETD8 Expression in neonatal rat lung and these effects are ameliorated by maternal DHA supplementation. Early Hum Dev 86(12):785-91, 2010. [PubMed]
  3. Baack, M, Norris, A, Yao, J, Colaizy, T. LONG CHAIN POLYUNSATURATED FATTY ACID LEVELS IN US DONOR BREASTMILK. PEDIATRIC RESEARCH 66(4):476-476, OCT 2009.
  4. Tseng, Y, Kokkotou, E, Schulz, T, Huang, T, Winnay, J, Taniguchi, C, Tran, T, Suzuki, R, Espinoza, D, Yamamoto, Y, Ahrens, M, Dudley, A, Norris, A, Kulkarni, R, Kahn, C. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature 454(7207):1000-4, 2008. [PubMed]
  5. Norris, A, Hirshman, M, Yao, J, Jessen, N, Musi, N, Chen, L, Sivitz, W, Goodyear, L, Kahn, C. Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle. Endocrinology 149(11):5374-83, 2008. [PubMed]
  6. Katic, M, Kennedy, A, Leykin, I, Norris, A, McGettrick, A, Gesta, S, Russell, S, Bluher, M, Maratos-Flier, E, Kahn, C. Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice. Aging Cell 6(6):827-39, 2007. [PubMed]
  7. Spector, A, Norris, A. Action of epoxyeicosatrienoic acids on cellular function. Am J Physiol Cell Physiol 292(3):C996-1012, 2007. [PubMed]
  8. Gesta, S, Blüher, M, Yamamoto, Y, Norris, A, Berndt, J, Kralisch, S, Boucher, J, Lewis, C, Kahn, C. Evidence for a role of developmental genes in the origin of obesity and body fat distribution. Proc Natl Acad Sci U S A 103(17):6676-81, 2006. [PubMed]
  9. Norris, A, Kahn, C. Analysis of gene expression in pathophysiological states: balancing false discovery and false negative rates. Proc Natl Acad Sci U S A 103(3):649-53, 2006. [PubMed]
  10. Norris, A, Svoren, B. Complications and comorbidities of type 2 diabetes. Pediatr Ann 34(9):710-8, 2005. [PubMed]