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Photo of Timothy Starner

Timothy Starner

Associate Professor,  Pediatrics

Contact Information

Phone: +1 319 335 7265
Email: timothy-starner@uiowa.edu
Web:

Education

BS, Psychology, Colorado State University
BS, Biological Sciences, Colorado State University
MD, Medicine, University of Colorado HSC
Residency, Pediatrics, University of Iowa
Fellowship, Pediatric Pulmonary, University of Iowa

Appointments

Primary: Pediatrics

Centers and Program Affiliations


Research Interests

asthma, cystic fibrosis, disease resistance, pediatrics, peptide

MeSH Terms from Publications

Haemophilus influenzae, Respiratory Mucosa, Cystic Fibrosis, beta-Defensins, Interleukin-8, Microbial Sensitivity Tests, Humans, Anti-Bacterial Agents, Trachea, Ileus, Lung, Antimicrobial Cationic Peptides, Drug Resistance, Bacterial, Gentamicins, Sputum, Pulmonary Disease, Chronic Obstructive, Biofilms, Genetic Complementation Test, Pseudomonas aeruginosa, Animals, Bronchoalveolar Lavage Fluid, Organ Culture Techniques, Bronchi, Interleukin-1, Cathelicidins

Research Summary

My clinical and research interests include asthma, cystic fibrosis, innate immunity of the lung, and interactions between antimicrobial peptides and bacteria.

Recent Publications


Show publications
  1. The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia. Am J Physiol Lung Cell Mol Physiol 300(1):L25-31, 2011. [PubMed]
  2. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Sci Transl Med 2(29):29ra31, 2010. [PubMed]
  3. Pseudomonas aeruginosa rugose small-colony variants have adaptations that likely promote persistence in the cystic fibrosis lung. J Bacteriol 191(11):3492-503, 2009. [PubMed]
  4. Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science 321(5897):1837-41, 2008. [PubMed]
  5. Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. Antimicrob Agents Chemother 52(1):137-45, 2008. [PubMed]
  6. Modulation of airway inflammation by Haemophilus influenzae isolates associated with chronic obstructive pulmonary disease exacerbation. Proc Am Thorac Soc 3(6):482-3, 2006. [PubMed]
  7. Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis. Am J Respir Crit Care Med 174(2):213-20, 2006. [PubMed]
  8. Pathogenesis of early lung disease in cystic fibrosis: a window of opportunity to eradicate bacteria. Ann Intern Med 143(11):816-22, 2005. [PubMed]
  9. Haemophilus influenzae from patients with chronic obstructive pulmonary disease exacerbation induce more inflammation than colonizers. Am J Respir Crit Care Med 172(1):85-91, 2005. [PubMed]
  10. Lysozyme secretion by submucosal glands protects the airway from bacterial infection. Am J Respir Cell Mol Biol 32(6):548-52, 2005. [PubMed]