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Alexandra Paige Davis Volk

This person no longer has an active appointment with the University of Iowa.


BA, Biochemistry and Chemistry, Cornell College
MD, Medicine, University of Iowa
Residency, Pediatrics, University of Iowa
Fellowship, Pediatric Critical Care, University of Iowa

Research Interests

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Research Summary

Recent Publications

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  1. Lamb FS, Hook JS, Hilkin BM, Huber JN, Volk APD, Moreland JG. Endotoxin priming of neutrophils requires endocytosis and NADPH oxidase-dependent endosomal reactive oxygen species. Journal of Biological Chemistry. 2012 Jan 10.  In Press.
  2. Volk, A, Barber, B, Goss, K, Ruff, J, Heise, C, Hook, J, Moreland, J. Priming of neutrophils and differentiated PLB-985 cells by pathophysiological concentrations of TNF-? is partially oxygen dependent. J Innate Immun 3(3):298-314, 2011. [PubMed]
  3. Volk, A, Heise, C, Hougen, J, Artman, C, Volk, K, Wessels, D, Soll, D, Nauseef, W, Lamb, F, Moreland, J. ClC-3 and IClswell are required for normal neutrophil chemotaxis and shape change. J Biol Chem 283(49):34315-26, 2008. [PubMed]
  4. Moreland, J, Davis, A, Matsuda, J, Hook, J, Bailey, G, Nauseef, W, Lamb, F. Endotoxin priming of neutrophils requires NADPH oxidase-generated oxidants and is regulated by the anion transporter ClC-3. J Biol Chem 282(47):33958-67, 2007. [PubMed]
  5. Femling, J, Cherny, V, Morgan, D, Rada, B, Davis, A, Czirják, G, Enyedi, P, England, S, Moreland, J, Ligeti, E, Nauseef, W, DeCoursey, T. The antibacterial activity of human neutrophils and eosinophils requires proton channels but not BK channels. J Gen Physiol 127(6):659-72, 2006. [PubMed]
  6. Moreland, J, Davis, A, Bailey, G, Nauseef, W, Lamb, F. Anion channels, including ClC-3, are required for normal neutrophil oxidative function, phagocytosis, and transendothelial migration. J Biol Chem 281(18):12277-88, 2006. [PubMed]