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2012 Research Week Translational Science Category Winners Announced

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Research Week is always an exciting time at the University of Iowa and we’d like to congratulate all of the poster presenters for producing such innovative and engaging work. It’s always a difficult decision to pick winners, and we are very proud of everyone’s efforts.

Congratulations to the winners of the 2012 Research Week translational category poster presentations:

  • Carver College of Medicine Graduate Student Levi Sowers from the Molecular and Cellular Biology Program and the Department of Pediatrics with his T1 poster PRICKLE2 null mice display abnormal synaptic morphology and autistic like behaviors.
  • Carver College of Medicine Graduate Student John Lee from the Department of Internal Medicine with his T1 poster Investigating the therapeutic effect of Rhes suppression in a mouse model of Huntington’s Disease.
  • College of Public Health Graduate Student in Toxicology Thomas van’t Erve, PhD from the with his T2 poster Concordance of Glutathione Metabolites in the Red Blood Cells of Mono-zygotic Twin Pairs: Implications for the RBC Storage Lesion.
  • Iowa State University Graduate Student Anamitra Ghosh from the Department of Biomedical Sciences with his poster Anti-inflammatory and Neuroprotective Effects of a Novel Compound Mito-apocynin in a Mouse Model of Parkinson’s Disease.
  • Adjunct Assistant Professor of Pediatrics Division of Child Neurology Bahri Karacy, PhD, from the Department of Pediatrics with his T2 poster Brain injury in congenital LCM virus infection is both virus-mediated and immune-mediated.
  • Program Consultant Jamie L’Heureux from the Department of Pediatrics with her T3 poster Development of a comprehensive DNA and tissue Biobank at the University of Iowa: The UI Biobank.

This was the third year that our colleagues from Iowa State University joined us for Research Week. This unique relationship illustrates the powerful potential of spawning and nurturing new collaborations between our campuses to help fulfill the ICTS mission of advancing healthcare in Iowa and beyond.

For a list of all individuals who entered posters in the ICTS translational categories, please see below.

T1

            College of Medicine Graduate Students

  • Amanda Decker (Anatomy & Cell Biology): Fishing trpm7. An ion channel needed for dopaminergic neuron survival
  • Christopher Groen (Anatomy and Cell Biology): Drosophila nurse cell dumping reveals a novel interaction between prostaglandin signaling and Fascin
  • Suraj Yalamuri (Anesthesia): Intrathecal Administration of Neuropeptide Y (NPY) is Analgesic after Plantar Incision
  • Maged Awadalla (Internal Medicine) Airway morphological abnormalities in the newborn cystic fibrosis pig affect airflow and particle distribution pattern
  • Megan Keiser (Internal Medicine): Therapies for Spinocerebellar Ataxia Type 1
  • Pavitra Narasimha (Internal Medicine): RNAi Therapy for Polyglutamine Expansion Disorders
  • Megan Kiedrowski (Microbiology): Staphylococcus aureus Extracellular Nucleases Have Anti-Biofilm Activity
  • Eric Kaiser (Molecular Physiology and Biophysics) Rizatriptan inhibits CGRP-induced light aversion behavior in C57BL/6J mice
  • Tyler Rasmussen (Molecular Physiology and Biophysics): Heart Art: Modulating Sinus Node Physiology and Disease by Gene Painting
  • Cory Massey (Neurology): Isoflurane inhibits serotonin (5-HT) neuron chemosensitivity in vitro and markedly decreases the hypercapnic ventilatory response in vivo
  • Arliss Dudley-Cash (Neuroscience): The Differential Effect of Low Concentration Capsaicin Infiltration on Incisional Pain
  • Kelsey  Whittier (Pediatrics, Graduate Program in Neuroscience): Differential G-Protein Coupled Receptor Expression in Medulloblastoma Subtypes
  • Rachel Starks (Pharmacology): Role for Bbs1 in Central Nervous System Regulation of Insulin Receptor Signaling
  • Gohar  Manzar (Biomedical Engineering): Ym1 is a Stem Cell Factor That Augments NK Cell Killing of Tumor Cells: New Paradigm for Tumor Treatment
  • Michael Hayes (Internal Medicine): Regulation of Malaria by Induced Pluripotent Stem (iPS) Cell Derived Transgenic T-cells
  • Collin Kreple  (Molecular Physiology and Biophysics): Loss of ASIC1a increases endogenous opioids, causes a dependence-like state, and enhances drug-seeking behaviors in mice
  • Colin Buzza (Psychiatry): Does carbon dioxide (CO2) inhalation increase fear memory in humans?

Postdoctoral Fellow/Resident

  • Joanne Avraam (Neurology): Effects of chronic nicotine exposure on cultured medullary 5-HT neurons
  • Preeyaphan Arunakul (Anesthesia): Effect of Capsaicin and Local Anesthetic nerve Blockade on Pain Behaviors Caused by Plantar Incision
  • U C Emerenini (Internal Medicine): αENaC Polymorphisms alter ENaC Current
  • Leah Reznikov (Internal Medicine): Novel Nervous System Phenotypes in Newborn Pigs with Cystic Fibrosis
  • Evan Rosenbluth (OB/GYN): Differential Expression of Micro-RNA in Day 5 Human Euploid and Aneuploid Blastocysts
  • Eun-Mi Kim (Internal Medicine): iPSCs are Rejected in Syngeneic Mice and Induce Immunological Rejection of ESCs
  • Grefachew Workalemahu (Internal Medicine): Novel phosphoantigens for human Vγ2Vδ2 T cells produced by Staphylococcus aureus and Streptococcus Gram-positive cocci using the mevalonate isoprenoid pathway

College of Pharmacy

  • Stacy Ross (Pharmaceutical Sciences and Experimental Therapeutics): Reducing Pseudomonas aeruginosa Biofilm Growth with Antibiotics and Nutrient Dispersion Compounds
  • Colin Higgins (Pharmaceutical Sciences and Experimental Therapeutics): Structural Analysis of RGS4 Inhibition: What Does it Mean for Parkinson’s Therapy?
  • Manar Al-Ghabeish (Pharmaceutics): Drug Transporters Expressedin the Nasal Epithelia   
  • Maya George (Pharmaceutics): The Role of Organic Cation Transporters (OCTs) in the Nose to Brain Delivery of Amantadine and Cimetidine
  • Kiran  Dhakal (Occupational and Environmental Health): Identification of 4-chlorobiphenyl metabolites in urine as a potential biomarker of human exposure of environmental  polychlorinated biphenyls (PCBs)

 Staff

  • R. Marshall Pope (Administration): Proteomic discovery and quantification with MS-based platforms
  • Richard Shields (Physical Therapy and Rehabilitation Science): Limb Segment Loading Modulates Post Activation Depression of Soleus H-reflex in Humans.
  • Kelly Messingham (Dermatology): Eosinophils in BP express FcεRI and BP autoantibodies trigger eosinophil degranulation
  • Richard Shields (Physical Therapy and Rehabilitation Science): Electrical and Mechanical Stimulation Regulate mRNA Expression in Human Paralyzed Muscle
  • Tanner Wallen (Department of Otolaryngology): Electro-olfactogram measurements of olfactory function in newborn cystic fibrosis pigs
  • Brett Wagner (Free Radical & Radiation Biology Program): Dissecting superoxide production by HL-60 cells using DHE and Spin trapping
  • Steven Kunkel (Internal Medicine): In Diet-induced Obese Mice, Ursolic Acid Increases Skeletal Muscle and Brown Fat and Reduces Obesity, Glucose Intolerance and Fatty Liver Disease
  • Michael Rector (Internal Medicine): Absence of cftr disrupts airway smooth muscle function in a porcine model of cystic fibrosis
  • Anna Reisetter (Internal Medicine): Smoking inhibits microRNA maturation via post-translational modification of Dicer
  • Frederick Blodi (Ophthalmology and Visual Sciences): Photoreceptors with no discs/lamellae can support useful vision in mice
  • Prescott Mackie (Internal Medicine): A new computer based method using bipolar electrogram changes to detect myocardial ischemia
  • Zhaowen Zhu (Internal Medicine): Biliverdin restores type I interferon signaling in cells expressing HCV NS3/4a protease
  • Mona Garvin (VA Center for the Prevention and Treatment of Visual Loss): A Structure-Structure-Based Correlation Map Using Spectral-Domain Optical Coherence Tomography Resembles Nerve Fiber Bundle Patterns in Glaucoma Subjects

T2

            College of Medicine Graduate Student

  • Christopher Kirkpatrick: Development of Pupillary Adrenergic Supersensitivity after Pharmacologic Induction of Oculosympathetic Defect

College of Pharmacy Graduate Student

  • Mohammad Alqudah (Pharmaceutical Sciences and Experimental Therapeutics): NOTCH3 as a Potential Predictive Biomarker in Malignant Glioma

Staff

  • Richard Shields (Physical Therapy and Rehabilitation Science): High-Resolution CT Analysis of Bone Adaptations to Electrical Stimulation Training after Spinal Cord Injury
  • Ergun Uc (Neurology): Aerobic Fitness, Cognition, and Brain Networks in Parkinson's Disease

T3

            College of Medicine Graduate Student

  • Annah Vollstedt (Infectious Diseases): Hansen’s Disease (Leprosy) in Nova Cruz, Brazil: Factors Correlating with the Risk of Disease
  • Elizabeth Leslie (Pediatrics): Comprehensive analysis of IRF6 mutations in families with Van der Woude syndrome and popliteal pterygium syndrome and public whole exome databases

            College of Pharmacy Graduate Student

  • Rowan AlEjielat (Pharmacy): Genetic variation and chemotherapy response in lymphoma patients

Staff

  • Ryan Carnahan (Epidemiology): Improving Antipsychotic Appropriateness in Dementia Patients:  Development of Clinical Tools and Training
  • Jennifer Rigdon (Pediatrics): FaceBase biorepository: A resource for craniofacial researchers
  • Marin Schweizer (Internal Medicine): Staphylococcus aureus Nasal Colonization is Not Associated with Mortality among Infected Patients: A Meta-Analysis

T4

College of Pharmacy Graduate Student

  • Janthima Methaneethorn (Pharmaceutical Sciences & Experimental Therapeutics): Modeling and Simulation to Evaluate Pyronaridine Exposure in Pediatric Malaria Patients

College of Public Health Graduate Student

  • Cara Hamann (Epidemiology): Matched case-control study of on-road bicycle facilities and bicycle crashes in Iowa, 2007-2010

Staff         

  • Michael Ohl (Internal Medicine): Diffusion of Innovation in HIV Therapy: Rural Residence and Raltegravir Adoption in an Equal-Access Healthcare System

Other Category

 College of Medicine Graduate Students

  • Babita Bisht (Internal Medicine): Effects of Intensive Directed Nutrition (IDN), Progressive Exercise Program (PEP) and Neuromuscular electrical stimulation (NMES) on secondary progressive multiple sclerosis (SPMS)
  • Andrew Ackell (Molecular Physiology & Biophysics): Oxidized CaMKII and Atrial Fibrillation: Does the Road to Atrial Arrhythmia Run Through the Mitochondria?

College of Medicine Postdoctoral Fellows/Resident

  • Peng Gao (Internal Medicine): Dynamic HoxB4 Regulatory Network During Embryonic Stem Cell Differentiation to Hematopoietic Stem Cell

Staff

  • Mollie Giller (Internal Medicine): Improving Osteoporosis Education of Patients with Printed Materials: A Mixed-Methods Pilot Study of a Bone Health Brochure
  • Jatin Vaidya (Psychiatry): Reduced neural sensitivity to anticipatory reward value in adolescents
  • Craig Morita (Internal Medicine): Innate Memory of Human Vγ2Vδ2 T Cells
  • Jinhua Xiang (Internal Medicine & VAMC):  Expression of GBV-C E2 Protein Motifs in a CD4+ T Cell Line (Jurkat) Inhibits HIV-1 Entry and Replication

Iowa State University Participants

Graduate Students

  • Samuel Buxton (Biomedical Sciences): Heterogeneity of parasitic nematode nicotinic acetylcholine receptors revealed by functional expression of Oesophagostomum dentatum levamisole receptors in Xenopus oocytes
  • Sreekanth Puttachary (Biomedical Sciences): Cholinergic receptors on the nematode pharynx; an unexploited drug target
  • Uri Donnett (College of Veterinary Medicine): An Epidemiological Study of Mycoplasma Species in Felines Utilizing a Novel Pan-Myco PCR Assay
  • Muhammet Ay (Biomedical Sciences): Molecular Cloning and Functional Characterization of  the Oxidative-Stress Sensitive Kinase PKD1 Gene Promoter in a Cell Culture Model of Parkinson’s Disease
  • Dong-suk Kim (Biomedical Sciences): Manganese Exposure Downregulates STAT5b to Compromise the Cellular Protective Mechanisms Against Manganese Neurotoxicity
  • Matthew Neal (Biomedical Sciences): Induction of prokineticin-2 and its neuroprotective effect against neurotoxic insult in dopaminergic neurons
  • Nikhil Panicker (Biomedical Sciences): Fyn kinase plays a role in manganese nanoparticle induced neuroinflammation  -Anti-inflammatory effects of Fyn kinase inhibitors rosmarinic and caffeic acids in Mn nanoparticle induced neuroinflammation
  • Dilshan Harischandra (Biomedical Sciences): Human α-Synuclein Protects Against Manganese Neurotoxic Insult During the Early Stages of Exposure in a Dopaminergic Cell Model of Parkinson’s Disease
  • Adam Herrick (Veterinary Microbiology and Preventative Medicine): Sero-Molecular Epidemiological Study of Influenza A Virus in Companion Animals

ISU Staff        

  • Albert Jergens (Veterinary Clinical Sciences): MT1E and S100 genes provide robust discriminative molecular signatures of intestinal inflammation in canine inflammatory bowel disease

 

Publish Date: 
Friday, April 6, 2012 - 09:25
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